maximum tolerated dose

基本解釋

The maximum tolerated dose? The minimum dose that leads to maximum inhibition of the target?
但什么是這些藥物的最佳劑量，最大耐受劑量，最大限度抑制目標的最小劑量？
In this paper, the estimation of the maximum tolerated dose of a drug for phase I clinical trials is investigated.
這篇論文主要研究的是第I階段臨床試驗中最大耐受劑量的估計問題。
To determine the maximum - tolerated dose (MTD) and dose - limiting toxicity (DLT) of iri-notecan (CPT-11), fluorouracil (5-FU), and leucovorin (CF) in patients with gastrointestinal cancers.
目的探索CPT-11（開普拓）聯(lián)合CF/5-FU治療胃腸道癌的最大耐受劑量（MTD）和劑量限制性毒性（DLT）。