refractory phase

基本解釋

Severe hepatotoxic events are also noted for an ongoing phase 1/2 combination study in pediatric patients with relapsed or refractory acute leukemia.
一項處于開展階段的在難治性或復發(fā)性急性白血病兒童患者中進行的合并用藥1/2期研究中，也發(fā)現(xiàn)嚴重的肝毒性事件。
We report the results of a phase II, single-arm, multicenter trial evaluating the safety and efficacy of lenalidomide oral monotherapy in patients with relapsed or refractory aggressive NHL.
我們在此報道一個II期多中心單一研究項試驗，以評價來那度胺口服單一療法治療復發(fā)性或難治性侵襲性NHL的安全性和有效性。
A phase 1 trial dose-escalation study of tipifarnib on a week-on, week-off schedule in relapsed, refractory or high-risk myeloid leukemia.
替匹法尼用一周，停一周劑量遞增治療復發(fā)性，難治性或高危髓細胞性白血病1階段試驗。