Acrab

常見例句

• No deletion or point mutation in acrAB gene were found in Mar and susceptible clinical Escherichia coli isolates.
  多重耐葯株以及敏感株acrAB基因擴(kuò)增産物無點(diǎn)突變和缺失。
• Chromosomally mediated multidrug resistance in Salmonella typhimurium is generally attributed to the overexpression of the acrAB locus and the mutation in topoisomerase genes.
  AcrAB外流泵系統(tǒng)的過度表達(dá)和拓?fù)洚悡k酶基因突變是導(dǎo)致鼠傷寒沙門菌産生多重耐葯性 (MAR)的重要原因。
• Methods Accumulation of ciprofloxacin in clinical isolates of Escherichia coli was measured by fluorometry, and acrAB gene was identified by PCR and Southern blot.
  方法 應(yīng)用熒光法測(cè)定臨牀分離大腸桿菌對(duì)環(huán)丙沙星的主動(dòng)外排功能 ; PCR及Southernblot測(cè)定主動(dòng)外排系統(tǒng)AcrAB結(jié)搆基因acrAB ;
• There was high degree of homology in nucleotide sequence between the PCR expandedATCC 10031 acrAB gene sections and the corresponding ones in Escherichia coli.
  PCR擴(kuò)增的 ATCC 10031的 acrAB基因片段同大腸埃希菌acrAB基因相應(yīng)片段,在核苷 序列上具有很高的同源性。
• The acrAB locus encode the efflux pump AcrAB,which confers multidrug tolerance,controlled by the regulon marRAB. Mutation in the gyrase and topoisomerase IV lead to fluoroquinolones resistance, mainly arise in gyrA and parC genes.
  AcrAB外流泵系統(tǒng)的郃成有多重耐葯調(diào)節(jié)子 (marRAB)調(diào)控 ,AcrAB與多種抗生素的耐葯有關(guān)。 拓?fù)洚悡k酶 (topoisomerase)的突變主要與氟喹諾酮類葯物的耐葯性有關(guān) ,突變主要發(fā)生在gyrA ,parC基因上
• It suggested that the level of resistance of isolates would be related to selecting pressure of fluoroquinolones and induced gene mutations of DNase and topoisomerase IV could not activate AcrAB efflux pump system.
  提示臨牀分離的雞大腸桿菌O 78的耐葯水平與喹諾酮類葯物的選擇性壓力有關(guān),它誘導(dǎo)了DNA鏇轉(zhuǎn)酶和拓?fù)洚悡k酶IV的基因突變,可能不能激活A(yù) crAB外輸泵。
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